TIMELINE
History of moderation of Cancer Treatments
3000 BC
First origin of
cancer was
discovered in
Egypt with
evidence from
books discuss-
ing removal of tumors, and with an end result of no cure.
1728-1793
John Hunter believed
certain (ones that
hadn't invaded tissue)
tumors could be
removed surgically.
1903
The first use of
Radiation was
used to treat
two Russian
patients who
had skin cancer, due to Marie Curie’s discovery of the element Radium
in 1898.
1960
Philadelphian researchers discover a chromosomal translocation seen in most Leukemias, which took scientist a step further to be the first genetic mutation to be targeted with a treatment known as Gleevec.
2003
The Human Genome is decoded which allows gene screening to look for cancer.
The Clinical Trials Cooperative Group Program is established by the U.S. National Cancer Institute due to screening it has brought breakthroughs in chemotherapy for breast and colon cancers.
Began to use
brachytherapy,
which is applying
little seed of
radiation usually
in prostate gland,
which only
affects tumor.
19th Century
Rudolf Virchow founded cellular pathology, and improved surgery (by telling surgeon if the operation had completely removed cancer) and allowed understanding of the damage cancer caused to an extent.
By using drug aminopterin, Sydney Faber is able to get the first ever partial remission, and then leads him to 10 more remission cases.
Rituximab is used for patients with B-cell non-Hodgkin lymphoma that no longer responds to other treatments (first FDA Targeted Cancer Drug).
1958
NCI Scientist think of using “Combination Chemotherapy” (a mixture of drugs) which leads to remission in both adult and children with acute Leukemia.
1977
By using cisplatin, vinblastine and bleomycin, it can cure 70 percent of patients with advanced testicular cancer (modern day cures 95%).
2009
Herceptin begins to show
benefit for breast cancer.
Targeted therapy such as immunotherapy, is starting to be one of the most precise medicine–based approaches. Immunotheray directly works as molecular targets, new types of treatment, and new combination to attack cancer.